NVP-2

NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584µM,0.706µM, and 0.605µM, respectively. NVP-2 induces cell apoptosis.

Product parameters
Product item	NVP-2
CAS number	1263373-43-8
Molecular weight	513.07
Molecular formula	C27H37ClN6O2
Specification	5mg，10mg，25mg，100mg，500mg，1g,10g
Traits	White to yellow powder
Design file	HNMR/HPLC/COA
Storage conditions	Powder: -20°C for 3 years \| In solvent: -80°C for 2 years
Delivery	3-5 days
Solubility	DMSO: 100 mg/mL (194.91 mM) ( < 1 mg/mL refers to the product slightly soluble or insoluble )
References	BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment - PubMed (nih.gov)
Shipment	By sea, By air, By express

公司信息.jpg

Hubei Chuchang Biotech Co.,Ltd. (CC-BIOTECH) is a scientific and technological enterprise which integrates R&D, production and sales. The company has established long-term cooperation with well-known pharmaceutical and chemical enterprises, scientific research institutions and university laboratories at home and abroad, and is committed to chemical customization synthesis, high value-added pharmaceutical intermediates and research and development of new drugs. It can provide customized production of products ranging from gram-scale for laboratory research, kilogram-scale to industrial ton-scale. At the same time, our company serves research institutes and colleges, provides active compounds and chemical reagents for scientific research, and accepts chemical custom synthesis.

Hubei Chuchang Biotech Co.,Ltd. covers pharmaceutical intermediates, API active compounds, polypeptide products, natural product molecules, high purity natural plant monomers,uv absorber,cosmetic product, scientific research reagents, biochemical reagents, chemical standard products, etc. At the same time, the company also accepts high purity compounds and monomers ordering business.

Since its establishment, the company has always adhered to the business concept of customer first and made continuous progress, which has won the high praise and trust of customers at home and abroad, such as universities, scientific research institutions and pharmaceutical and chemical enterprises, and established long-term and stable business relations with them. The company will continue to provide customers with better products and services with strict quality management system and stable product quality.