Welcome: Hubei Chuchang Biotech Co.,Ltd.

GSK215

GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader (pDC50= 8.4). GSK215 is designed by the FAK inhibitor VS-4718 and a binder for the VHL E3 ligase. GSK215 can induce rapid and prolonged FAK degradation.

Product parameters

                    Product item

 GSK215

                    CAS number

 2743427-26-9

                    Molecular weight

 985.13

                    Molecular formula

 C50H59F3N10O6S

                   Specification

 5mg,10mg,25mg,100mg,500mg,1g,10g

                    Traits

 Off-white to light yellow powder   

                    Design file

 HNMR/HPLC/COA

                    Storage conditions

 Powder: -20°C for 3 years | In solvent: -80°C for 2 years

                    Delivery

 3-5 days

                    Solubility

DMSO: 225.0 mg/mL (228.4 mM ), Need ultrasonic

( < 1 mg/mL refers to the product slightly soluble or insoluble )    

                    References

Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs - PubMed (nih.gov)

                    Shipment

 By sea, By air, By express


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Hubei Chuchang Biotech Co.,Ltd. (CC-BIOTECH) is a scientific and technological enterprise which integrates R&D, production and sales. The company has established long-term cooperation with well-known pharmaceutical and chemical enterprises, scientific research institutions and university laboratories at home and abroad, and is committed to chemical customization synthesis, high value-added pharmaceutical intermediates and research and development of new drugs. It can provide customized production of products ranging from gram-scale for laboratory research, kilogram-scale to industrial ton-scale. At the same time, our company serves research institutes and colleges, provides active compounds and chemical reagents for scientific research, and accepts chemical custom synthesis.

     Hubei Chuchang Biotech Co.,Ltd. covers pharmaceutical intermediates, API active compounds, polypeptide products, natural product molecules, high purity natural plant monomers,uv absorber,cosmetic product, scientific research reagents, biochemical reagents, chemical standard products, etc. At the same time, the company also accepts high purity compounds and monomers ordering business.

     Since its establishment, the company has always adhered to the business concept of customer first and made continuous progress, which has won the high praise and trust of customers at home and abroad, such as universities, scientific research institutions and pharmaceutical and chemical enterprises, and established long-term and stable business relations with them. The company will continue to provide customers with better products and services with strict quality management system and stable product quality.

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Contact: Mr.Ren

Phone: 15623560702

Tel: 86-15623560702

Email: info@chuchangbiotech.com

Add: Chuangye Street, Hongshan District,Wuhan,Hubei Province,China.