Welcome: Hubei Chuchang Biotech Co.,Ltd.

dTRIM24

dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC.

Product parameters

                    Product item

 dTRIM24

                    CAS number

 2170695-14-2

                    Molecular weight

 1113.3

                    Molecular formula

  C55H68N8O13S2

                    Specification

  5mg,10mg,25mg,100mg,500mg,1g,10g

                    Traits

  White to off-white powder              

                    Design file

  HNMR/HPLC/COA                

                    Storage conditions

  store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 2 years               

                    Delivery

   3-5 days              

                    Solubility

Ethanol: insoluble

DMSO: 90.0 mg/mL (80.8 mM ), Need ultrasonic

( < 1 mg/mL refers to the product slightly soluble or insoluble )             

                    References

1. Gechijian LN, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018 ; 14(4):405-412.

2. Huang JH, et al. Bioinspired PROTAC-induced macrophage fate determination alleviates atherosclerosis. 2023 ; 1-153. Han M, et al. Pharmacological targeting of Tripartite Motif Containing 24 for the treatment of glioblastoma. J Transl Med. 2021 ; 19(1):505.

                    Shipment

   By sea, By air, By express


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Hubei Chuchang Biotech Co.,Ltd. (CC-BIOTECH) is a scientific and technological enterprise which integrates R&D, production and sales. The company has established long-term cooperation with well-known pharmaceutical and chemical enterprises, scientific research institutions and university laboratories at home and abroad, and is committed to chemical customization synthesis, high value-added pharmaceutical intermediates and research and development of new drugs. It can provide customized production of products ranging from gram-scale for laboratory research, kilogram-scale to industrial ton-scale. At the same time, our company serves research institutes and colleges, provides active compounds and chemical reagents for scientific research, and accepts chemical custom synthesis.

     Hubei Chuchang Biotech Co.,Ltd. covers pharmaceutical intermediates, API active compounds, polypeptide products, natural product molecules, high purity natural plant monomers,uv absorber,cosmetic product, scientific research reagents, biochemical reagents, chemical standard products, etc. At the same time, the company also accepts high purity compounds and monomers ordering business.

     Since its establishment, the company has always adhered to the business concept of customer first and made continuous progress, which has won the high praise and trust of customers at home and abroad, such as universities, scientific research institutions and pharmaceutical and chemical enterprises, and established long-term and stable business relations with them. The company will continue to provide customers with better products and services with strict quality management system and stable product quality.

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Contact: Mr.Ren

Phone: 15623560702

Tel: 86-15623560702

Email: info@chuchangbiotech.com

Add: Chuangye Street, Hongshan District,Wuhan,Hubei Province,China.